Histopathological and Physiological Study of Nerium oleander and Lead on the Liver in the Male Albino Mice.

The current study prepareded to evaluate histopathological and some physiological parameters changes after treated with Nerium oleander L lead. Thus concentrated on tissue structures in the liver aqueous extract of lead solution. Its caused intense flaws albino mice. After expiration experimental time, blood specimens collecting value Aspartate Transaminase (AST), Alanine (ALT), urea (BUN) creatinine (CR-S) treatmented animals, then animals sacrificed for histopatolological results present noted remarkable parenchyma, these included acute cellular destruction hemorrhage. effects showed clear space between hepatocyte tissue, no prominent hepatic cords, most didn’t have normal nuclei. Physiological alterations observed significantaly increased enzymes (Aspartate Transaminase, ) when exposure Oleander compared control group.